Now we will talk about asthma and one of the very important question the genetic side of this disease as you know, The dawn of the new century has seen a revolution in our understanding of the
genetic basis of common diseases such as obesity, diabetes, heart disease,
cancer - pathogenenetics -, and neuropsychiatric conditions. These diseases are termed ‘complex
genetic diseases’ as they result from the effect of multiple genetic and interacting environmental factors Like these other common conditions, the role of a heritable component to susceptibility to allergic disease has long been recognized, with atopy and the clinical manifestation of allergy such as asthma and atopic dermatitis resulting from the interaction between an individual’s genetic make-up and their environmental exposures. Recent years have seen considerable progress in unravelling the contribution of specific genetic factors to an individual’s susceptibility, subsequent development, and severity of allergic disease. This has resulted in increasing insight into novel areas of allergic disease pathophysiology. Furthermore, studies of gene–environment interaction have lead to greater insight into the importance of environmental triggers for the initiation, exacerbation, and persistence of allergic diseases. i will develop this soon
genetic basis of common diseases such as obesity, diabetes, heart disease,
cancer - pathogenenetics -, and neuropsychiatric conditions. These diseases are termed ‘complex
genetic diseases’ as they result from the effect of multiple genetic and interacting environmental factors Like these other common conditions, the role of a heritable component to susceptibility to allergic disease has long been recognized, with atopy and the clinical manifestation of allergy such as asthma and atopic dermatitis resulting from the interaction between an individual’s genetic make-up and their environmental exposures. Recent years have seen considerable progress in unravelling the contribution of specific genetic factors to an individual’s susceptibility, subsequent development, and severity of allergic disease. This has resulted in increasing insight into novel areas of allergic disease pathophysiology. Furthermore, studies of gene–environment interaction have lead to greater insight into the importance of environmental triggers for the initiation, exacerbation, and persistence of allergic diseases. i will develop this soon
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